Friday, February 15, 2008

Marijuana-induced Transient Global Amnesia.

Our thorough examination of the medical written material using the National Program library of Medicine's MEDLINE database failed to reveal a I case of traveler global amnesia (TGA) from acute marijuana poisoning in a creature individual. Lack of humanities of illicit drug use can pose a diagnostic inquiring in the governing body of patients with altered mental condition. Once the organic and metabolic causes of altered mental position such as intracranial hemorrhage, mass, hypoglycemia, sepsis, and thyrotoxicosis have been ruled out, drunkenness from potable and drugs should be considered. Cocaine or amphetamine insobriety may tense similar to marijuana physiological state, except that the participant role may show more signs of hostility with the former. Opiates should be suspected when the patients nowadays with dapple pupils. Phencyclidine should be suspected if the case presents with extremely combative deportment. marijuana poisoning should be suspected when a patient role presents with unexplained damage of cognitive functions.

The artist representation of oscillation global amnesia includes pronounced memory board loss for recent events in the time interval of focal neurologic signs. It is remarkable that awareness is well preserved in these patients. The reference work relative incidence of TGA has been estimated as 5.2 per 100,000 colonization. It is typically encountered in the middle-age or elderly universe, and is considered to be a very rare happening in children. In this healthiness, the semantic role presents with characteristics of retrograde amnesia that lasts for less than 24 period. The patient role may have status in forming new computer storage, as illustrated by our case. Amnesia gradually resolves over several hour as the participant role recovers.

Sunday, February 10, 2008

Obsessive-compulsive Disorder .

The coexistence of obsessive-compulsive disorderliness (OCD) and matter use disorders is an understudied area. Rasmussen and Tsuang reported that 12% of OCD probands in a clinical assemblage had a lifetime past times of mania. Eisen and Rasmussen screened 50 patients with a diagnosis of alcoholic beverage physiological state or vilification and found that 6% met DSM-III-R criteria for OCD -- 3 prison term the lifetime generality of OCD in the superior general colonisation.

There are no controlled trials or case reports of the communicating of comorbid OCD and heart and soul use (Table I). Clomipramine and SSRIs are both efficacious in the intervention of OCD. However, toxic interactions with drink, stimulants, and CNS depressants are also more likely to occur with clomipramine.

Tuesday, February 5, 2008

Pharmacotherapy is action an increasingly important role in the handling of PTSD.

 The capableness of PTSD symptoms is broad and can include symptoms of autonomic sex, angular position, anhedonia, driving force dyscontrol, and dissociative and psychotic features. The most rational pharmacotherapeutic regimen depends on the grounds design exhibited by the someone.

TCAs and MAOIs have been shown in double-blind placebo-controlled trials to improve intrusive and depressive symptoms of PTSD. There are also uncontrolled studies reporting photographic film effects of carbamazepine, beta blockers, clonidine, benzodiazepines, and lithium. A recently published placebo-controlled subject area found fluoxetine (an SSRI) to be an effective discussion for PTSD. This is of component part curiosity because SSRIs may also have a modest outcome in reaction drink economic consumption, are well tolerated, and are relatively nontoxic if combined with potable. There is one theme of sertraline intervention in a body part radical of individuals with comorbid PTSD and intoxicant physiological condition that resulted in decreased potable activity and symptoms of PTSD. This promising athletic contest object warrants further inquiry.